PDO threads are an amazing product that are used in some of the leading minimally-invasive cosmetic treatments on the market. They are prized for how quick the treatment takes, the minimal to no downtime and recovery time, accessibility and affordability, and — most importantly — the amazing natural results they produce.
Today, PDO threads are in high demand from people who wish to reverse the signs of aging in their face. They can treat everything from sagging and drooping skin, to fine lines and wrinkles, to lack of definition and more.
There are other cosmetic treatments that address some of the same concerns in different ways. Two popular ones are Platelet-Rich Plasma (PRP) and the more advanced Platelet-Rich Fibrin (PRF).
A common question people have when they’re considering how best to address their aging concerns is whether PDO threads can be combined with other treatments such as PRP or PRF to maximize the results.
We’ll discuss this topic in more depth below, starting with descriptions of each of the three treatments.
Not only can you combine PDO threads with PRP or PRF treatments, but it is actually common for people to do so. By combining treatments, people are able to maximize the anti-aging results that they get.
Medically reviewed by: Elizabeth Williams RN
Updated: 6/19/2025
What Are PDO Threads Treatments?
PDO threads are thin sutures that are naturally dissolvable. They are made from a synthetic material that is 100% biocompatible, meaning there’s a very low risk for complications.
They’re also 100% biodegradable, which means the body will use natural processes to break them down over time.
PDO threads are inserted into your skin using a preloaded cannula, which is very similar to an IV line. They have barbs on the end of them that grab onto parts of your skin, which allows your provider to reposition it so you can achieve that youthful look you may have lost.
To break down the threads once the treatment is done, your body will produce extra collagen in the area. This helps extend the life of the treatment, and also makes your skin more elastic, smooth and youthful-looking.
What Are PRP and PRF Treatments?
PRP and PRF treatments are very similar. In fact, PRF is really known as a more modern and updated version of PRP.
PRP treatments are done by taking a sample of your blood and putting it into a centrifuge so that the platelets can be isolated. Your provider will then create a serum with the platelets, which will then be injected back into your skin.
Platelets are growth stimulants that occur naturally in your body, and they help to promote regeneration by also producing collagen. The idea, then, is that injecting the platelets back into your skin will help to create extra collagen to create similar results to PDO threads.
PRF treatments use a mix of your blood that contains white blood cells, fibrin and platelets. All of these things play vital roles in healing and tissue regeneration.
Unlike PRP, PRF doesn’t include any anticoagulants, which allows the growth factors to be released more slowly in a more sustainable way. This is meant to enhance the rejuvenating effects that the treatment can have on your skin.
| Timeframe | PDO Threads | PRP | PRF |
|---|---|---|---|
| Immediately Post-Treatment | Visible lift | Mild redness | Mild swelling |
| 1 Week | Healing begins | Initial glow | Subtle firming |
| 1 Month | Tightening increases | Collagen begins forming | Gradual rejuvenation |
| 3 Months | Peak collagen effect | Peak results | Sustained improvement |
| 12+ Months | Gradual fade | Repeat advised | Optional repeat |
Can You Combine PDO Threads with PRP or PRF Treatments?
Not only can you combine PDO threads with PRP or PRF treatments, but it is actually common for people to do so. By combining treatments, people are able to maximize the anti-aging results that they get.
The PDO threads can be used to lift parts of your skin and add definition around your mouth, for example, and directly address fine lines and wrinkles — things that PRP or PRF treatments simply can’t do.
Getting the PRP or PRF treatments on top of the PDO threads can help to enhance the production of collagen even more, which can have positive results in multiple ways. First, it can help to enhance the natural, youthful look that many people lose when they age, and second, it can help to extend the life of the results even longer.
The results of the treatments will begin to appear gradually over time. While they will fade, they typically last at least a year or more.
If you ever become dissatisfied with the results in the future, the good news is that you can repeat all these treatments to produce the results you’re looking for.
| Benefit | PDO + PRP | PDO + PRF |
|---|---|---|
| Collagen Production | Increased | Sustained Increase |
| Skin Texture | Improved | Significantly Improved |
| Result Longevity | Up to 18 months | Up to 2 years |
| Tissue Healing | Moderate | Enhanced |
Choose a Provider Who Uses V Soft Lift’s PDO Threads
PDO threads are an extremely versatile cosmetic treatment that are extremely effective at addressing the signs of aging. When combined with PRP and PRF treatments, patients can experience enhanced, well-rounded results that last even longer.
It’s always important to choose a provider who has experience in all of these treatments and who has a good reputation. It’s equally as important to choose one who uses the highest-quality PDO threads on the market, such as the ones produced by V Soft Lift.
The quality of our PDO threads are unmatched, as are the available choices in products for providers. We have produced a long line of threads so that providers can pick the ones that are best suited for each individual treatment and patient’s skin type.
For more information, contact us today.
