Advancements in medicine and technology have made body transformations possible without having to undergo invasive and expensive surgery that comes with long-term recovery periods and potential complications.
Weight loss medications have become extremely popular in recent years, as they have delivered amazing results for people who face challenges dropping pounds through diet and exercise alone.
While there are a lot of major benefits people can realize from taking these GLP-1 medications, there are some potential downsides, too. A major one is the fact that losing a significant amount of weight in a short period of time by taking these medications can cause skin to sag and loosen, or result in a loss of volume, especially in your face.
In this article, we’ll describe how patients can combine GLP-1 drugs and PDO threads to achieve skin tightening.
Luckily, this skin laxity can easily and effectively be addressed by PDO threads. These minimally-invasive cosmetic treatments have been used for years to help people improve some of the most common signs of aging, including lack of definition, fine lines and wrinkles, and drooping or sagging skin in the face.
Medically reviewed by: Elizabeth Williams RN
Updated: 8/26/2025
What Are GLP-1 Drugs?
GLP-1 drugs are popular medications that help people lose weight. Medically known as glucagon-like peptide-1, these medications are essentially hormones that can help to regular a person’s appetite and blood sugar levels.
These medications work by mimicking the hormone, which is naturally occurring in the body. What this does is delay the emptying of your stomach, which can make you feel like you’re fuller for a longer period of time, which in turn helps to reduce cravings and hunger.
GLP-1 drugs can also help to stabilize your body’s insulin levels. In fact, they were originally developed to help people manage their type 2 diabetes.
But, these popular medications such as tirzepatide (Zepbound and Mounjaro) and semaglutide (Ozempic, Wegovy and Rybelsus) are today used primarily to help qualified patients lose weight in a way in which they can be monitored by a doctor to ensure safety.
While these drugs have proven very effective at rapid weight loss, they can also result in negative effects such as skin laxity.
How to Address Skin Laxity Caused by GLP-1 Drugs with PDO Threads
While weight loss is obviously a good thing, no one wants the possible side effects of skin laxity. This can present itself in a number of ways on people, from sagging and loose skin to loss of volume.
Unfortunately, one of the most common places that this happens is in your face — which is obviously hard to hide. Unlike loose or sagging skin in your stomach, for example, you can’t cover your face with clothes.
Luckily, this skin laxity can easily and effectively be addressed by PDO threads. These minimally-invasive cosmetic treatments have been used for years to help people improve some of the most common signs of aging, including lack of definition, fine lines and wrinkles, and drooping or sagging skin in the face.
They can also be used to help correct the ill-effects of weight loss from GLP-1 drugs.
PDO threads are thin dissolvable sutures that are inserted into your skin via a preloaded cannula in a similar way to how an IV line is inserted. Certain types of PDO threads have barbs on them that grab onto parts of your skin and lift it up.
This mimics the results of a traditional facelift, without having to undergo invasive surgery. The treatments only require local numbing agents, are typically completed in less than an hour and come with a very short recovery time.
The threads are made of a synthetic material that is 100% biocompatible and biodegradable. This means there’s a low chance of any risks and that your body will fully break down and absorb the threads over time using natural processes.
In addition to the immediate lifting effects that the treatment can provide, you’ll also see longer-term effects from the extra collagen that’s produced by your body to break down the threads. This collagen will help make your skin tighter and glow more in a good way.
While PDO threads treatments are not permanent, they can be repeated at any time to achieve your desired results. That’s why combining GLP-1 drugs and PDO threads for skin tightening is so effective.
| Aspect | GLP-1 Drugs | PDO Threads |
|---|---|---|
| Purpose | Weight loss | Skin tightening |
| Method | Prescription medication | Minimally invasive sutures |
| Benefits | Reduces appetite, stabilizes insulin, rapid weight loss | Lifts sagging skin, stimulates collagen, non-surgical |
| Side Effects | Loose/sagging skin, volume loss | Temporary swelling, mild bruising |
| Best When Combined | With PDO threads for skin tightening | After GLP-1–induced weight loss |
Make Sure You Get a PDO Thread Treatment with V Soft Lift’s Products
GLP-1 medications have proven very effective at helping people lose weight. Yet, they often result in loose and sagging skin.
By combining these drugs with PDO thread treatments, though, you can help correct some of the ill effects of the sudden weight loss.
As you search for a provider for your PDO thread treatments, make sure that they are experienced in the field and reputable. Also make sure that they only use the best PDO threads available, such as those from V Soft Lift.
We have created a long line of high-quality PDO threads that have been fully FDA cleared for use in the U.S. Providers can choose from the different products we have created so each patient gets ones that are catered specifically to their skin type, skin condition and treatment — all of which ensures optimal results.
For more information, contact us today.